Source: ALL

Gene Gene Full Name DSI g DPI g pLI Disease Type Score gda EL gda EI gda N. PMIDs N. SNPs gda First Ref. Last Ref.
Entrez Id: 351
Gene Symbol: APP
APP 		amyloid beta precursor protein 0.422 0.846 4.7E-02
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.100 None 0.984 123 1 1988 2020
Entrez Id: 1859
Gene Symbol: DYRK1A
DYRK1A 		dual specificity tyrosine phosphorylation regulated kinase 1A 0.533 0.769 1.00
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.300 None 0.991 109 0 1996 2020
Entrez Id: 2623
Gene Symbol: GATA1
GATA1 		GATA binding protein 1 0.483 0.808 0.95
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.400 None 0.981 104 0 2002 2020
Entrez Id: 60
Gene Symbol: ACTB
ACTB 		actin beta 0.325 0.923 0.99
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.100 None 1.000 13 0 1999 2020
Entrez Id: 2078
Gene Symbol: ERG
ERG 		ETS transcription factor ERG 0.453 0.808 0.96
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.100 None 1.000 11 0 1996 2020
Entrez Id: 627
Gene Symbol: BDNF
BDNF 		brain derived neurotrophic factor 0.345 0.923 0.66
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.070 None 1.000 7 0 2006 2020
Entrez Id: 4204
Gene Symbol: MECP2
MECP2 		methyl-CpG binding protein 2 0.414 0.846 0.89
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.050 None 1.000 5 1 2004 2020
Entrez Id: 3586
Gene Symbol: IL10
IL10 		interleukin 10 0.281 0.923 5.9E-03
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.030 None 1.000 3 0 2005 2020
Entrez Id: 3557
Gene Symbol: IL1RN
IL1RN 		interleukin 1 receptor antagonist 0.373 0.923 3.1E-02
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.020 None 1.000 2 0 2011 2020
Entrez Id: 3558
Gene Symbol: IL2
IL2 		interleukin 2 0.336 0.885 0.48
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.020 None 1.000 2 0 1991 2020
Entrez Id: 9401
Gene Symbol: RECQL4
RECQL4 		RecQ like helicase 4 0.496 0.808 3.3E-35
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.010 None 1.000 1 0 2020 2020
Entrez Id: 55556
Gene Symbol: ENOSF1
ENOSF1 		enolase superfamily member 1 0.617 0.654 9.0E-19
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.010 None 1.000 1 1 2020 2020
Entrez Id: 406978
Gene Symbol: MIR199B
MIR199B 		microRNA 199b 0.588 0.615
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.010 None 1.000 1 0 2020 2020
Entrez Id: 23452
Gene Symbol: ANGPTL2
ANGPTL2 		angiopoietin like 2 0.545 0.731 1.5E-03
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.010 None 1.000 1 0 2020 2020
Entrez Id: 1621
Gene Symbol: DBH
DBH 		dopamine beta-hydroxylase 0.511 0.846 3.3E-10
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.010 None 1.000 1 0 2020 2020
Entrez Id: 406952
Gene Symbol: MIR17
MIR17 		microRNA 17 0.459 0.846
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.010 None 1.000 1 0 2020 2020
Entrez Id: 10097
Gene Symbol: ACTR2
ACTR2 		actin related protein 2 0.659 0.654 1.00
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.010 None 1.000 1 0 2020 2020
Entrez Id: 5063
Gene Symbol: PAK3
PAK3 		p21 (RAC1) activated kinase 3 0.569 0.731 0.99
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.010 None 1.000 1 0 2020 2020
Entrez Id: 28954
Gene Symbol: REM1
REM1 		RRAD and GEM like GTPase 1 0.531 0.885 5.3E-08
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.010 None 1.000 1 0 2020 2020
Entrez Id: 57379
Gene Symbol: AICDA
AICDA 		activation induced cytidine deaminase 0.463 0.885 9.2E-06
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.010 None 1.000 1 0 2020 2020
Entrez Id: 1827
Gene Symbol: RCAN1
RCAN1 		regulator of calcineurin 1 0.572 0.808 1.7E-02
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.400 None 0.965 57 0 1995 2019
Entrez Id: 4524
Gene Symbol: MTHFR
MTHFR 		methylenetetrahydrofolate reductase 0.337 0.885 3.2E-10
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.400 None 0.878 49 4 1999 2019
Entrez Id: 348
Gene Symbol: APOE
APOE 		apolipoprotein E 0.338 0.962 1.9E-03
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.100 None 0.955 44 1 1994 2019
Entrez Id: 861
Gene Symbol: RUNX1
RUNX1 		RUNX family transcription factor 1 0.425 0.808 0.65
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.100 None 0.970 33 0 1997 2019
Entrez Id: 174
Gene Symbol: AFP
AFP 		alpha fetoprotein 0.429 0.885 1.1E-11
CUI: C0013080
Disease: Down Syndrome
Down Syndrome 		disease 0.100 None 0.969 32 0 1986 2019